Gravel properly prepared for the aquarium

As substrate, virtually any gravel or sand from the hardware store can be used because the gravel and sand from the aquarium trade is also nothing else. No matter how one relates of the gravel, it must be washed even if on the package it is already washed. This is especially observed in the gravel in the pet trade case. Washing the soil substrate is still somewhat expensive and requires a lot of time especially if you wash >50kg aquarium gravel or sand. Therefore, it is a must for aquariums from about 200 liters. It is best suited for the soil substrate as a bricklayer tub (grout trough) wash, which is obtained at the hardware store from 5 euros. Of course, it can all make buckets summarize the approximately 15 liters, but it comes with a masonry trough a lot faster because in one run, it is more like gravel or sand clean.

The vessel with which you want to clean the ground floor is filled with only the best with much gravel that you later get when the vessel is filled with water. You should stir it well. It makes no sense to make it full because the more it is then the substrate should be stirred and the water becomes dirty faster and you may need to wash 2 times to change the water which is also again more effort. So, less is often more. When the right amount of sand or gravel is in the tank now, then you can fill it with water and then stir vigorously. The sand is clean and you can tell because when you cut out a small sample and then into a glass of clean water, they are then allowed to clear the muddy water which is no longer really something but not too much. After it has recently been stirred and then you can do without it. If it is clean enough and one has been agitated the sand, then you should empty the majority of the dirty water immediately before the dirt particles settle on the sand again. Then you can remove the remaining sand / gravel with a sand box strainer for children from the jar and rinse again briefly. The whole effort is very important because one should have very clean sand and gravel in the aquarium. One in advance, does not know what sand or gravel has everything on themselves, such as germs, toxins, pollen, and others. It is however important that the sand should not be washed at home or in the house because even the individual grains of sand or gravel can accumulate in the drain to a partial blockage or even cause complete blockage.

Ways to Found a MLM Business

There are various ways to establish a business or an industry. Here are the most important ones explained briefly in order for you to get an idea about the possibilities. Think carefully, do your research and find the way that suits you best. It is up to you to choose one of the different types of founding.

The founding of a new industry

Here you have everything in hand. You can build up your own name and use your creativity. You have to spend very much time and effort to get customers. There are no prejudices among customers but also no positive experiences. The curiosity of people is great and you have to use it to your advantage. In this case, it depends on how the customer responds to your idea.

The acquisition of a business

The acquisition of a business gives you the advantage of not having to build a reputation as your MLM business already has one. The customer base and the partnerships have already been initiated. It is much easier to buy a business because there are many aspects that you do not have to waste any more time with. It is important to ask exactly what the business is based on, whether it is popular among customers and what its financial situation is. You may have to pay quite some money if all these things are positive. Not only the products but also the customers, the position on the market and the partnerships have to be taken into considered.

Involvement in a company

You can get involved in as many companies as you want. This kind of independence is targeted mainly by people with money. You may be able to offer the company something it needs like MLM training and thus make your involvement count. The reputation has already been built, the business runs and you also have a customer base at your disposal.

Additional income through self-employment

Many people want to take up a second job or build a business outside of their everyday job. This way, you always have a job no matter what happens. You can learn and analyze everything in peace and you can earn your living if the business generates some profit. It all depends on how serious you are.

Franchising
 
The founding of a trade can bring many problems with it, so franchising is one of the best solutions for you. Probably paradoxically, franchises offer you many opportunities to become independent:
You take over the business idea of a franchise dealer, practice and attend it regularly. Your corporate design options are moving within a fixed frame.

Develop your own franchise system. The business idea has already proven successful, so all you have to do is to put it in practice. Then you can convince other people to follow your example and so on.

As a master franchisor, you get a license from foreign franchise companies that want to establish themselves on the American market. So you enter the national market as a franchisor and you acquire additional franchises on your own account.

The franchise process is centered on the franchisor, the trademark, the know-how and marketing. These are the main poles of developing a franchise. You get all the information and the tips against a fee. Of course, this limits your creativity and initiative.

E-business

This form of independence is unique. You have the possibility to choose any of the aforementioned types of business foundation, but you still choose this one? Then, you are probably doing this because you can choose whatever profession you want. This topic is very extensive, so it should be discussed separately. There are a lot of articles on the internet about how to build an e-business.

These are only the most important ways to fund a business. Spin-off funding, liberal professions, cooperation, multilevel marketing and business transfers are some of your other alternatives. Each form has its pros and cons. Therefore, you have all the motivation you need to choose self-employment.

Know Anatomy the Thymus

Synonym: Sweetbread

Definition

 

The thymus is a single pair of lymphoid organs located in the front part of the mediastinum. Thus, it is located above the heart and behind the sternum. The thymus is on both sides of the pleura. Usually, it develops from the third pharyngeal pouch. It is called the primary lymphoid organ because it is responsible for the primary development of T cells.

Structure and function

 

This organ has two asymmetric flaps, which are connected through connective tissue. The size of the thymus is dependent on age. It reaches its maximum size in childhood and weighs 30 g. The involution begins after puberty, when it is replaced by fat tissue. In adults, the thymus has an average weight of 18 g. This is often referred to as the retrosternal fat pad.
The thymus is situated in a cell-rich crust and can be viewed through a microscope. There are the typical Hassall's corpuscles of the thymus, which are an onion-like enrichment of epithelial cells (surface cells). Their function is not yet clear. In contrast, the cortex contains thymocytes. Therefore, the thymus is the only lymphoid organ that is also called a lymphoepithelial organ.

The thymus plays an important role in the development and differentiation of immune cells, called T cells. It is a kind of training ground for these cells. Immature cells that are formed in the bone marrow migrate into the thymus through the blood vessels. There they turn into thymocytes. Then they migrate through the cortex after several divisions of the thymic mark. This way they mature and develop T-cell receptors, which allow them to recognize antigens. There can be a negative selection and a positive one in the maturation process, depending on whether the antigens involved are endogenous or exogenous. First there is a positive selection. In this case, only those cells develop that have a so-called peptides receptor, but do not strongly bind to the MHC molecules. Then there is a negative selection, which ensures that the T-cell structures do not attack the body's own cells (self-tolerance). All cells that do not meet criteria die by programmed cell death (apoptosis). Just 5-10% of all T cells survive the maturation process. Only these cells reach the lymphoid organs and then colonize. Besides functioning as an immune organ, the thymus also acts as a hormone. The mediators it produces - thymosin, thymic and thymopoetin - influence the maturation of immune cells in the lymphoid organs.

Thymectomy

 

In children, the surgical removal of the thymus (thymectomy) causes impairment in the development of the immune system. However, this is the best way to eliminate the symptoms of myasthenia gravis. This is an autoimmune reaction against receptors on the motor plate of the muscles that leads to progressive muscle weakness. About half of patients with myasthenia gravis present an enlargement of the thymus, which is usually a thymoma (usually a benign tumor). Therefore, the autoimmune reaction is amplified as tumor cells have antigens similar to the muscle receptors. Therefore, patients can be relieved of the essential complaints through the surgical removal of the thymus.

The DiGeorge syndrome

 

The DiGeorge syndrome refers to an impaired development of the third and fourth pharyngeal pouches, which are normally formed during the embryonic development. The thymus is formed mainly from the third pharyngeal pouch, so an under-development of this organ can even cause the absence of the thymus. Other structures can also be affected, such as the parathyroid glands, teeth or throat muscles. The reduced or lack of training for T-cell patients leads to more or less severe immune defects. The most frequently encountered are heart defects, short stature and a general developmental disorder. The goal of therapy is a reduced exposure of patients to potentially immunostimulatory microorganisms. Therefore, hand disinfection and even face masks are important measures, as well as a well-developed vaccination schedule supplemented by antibiotic therapy. In principle, patients can also have a T-cell transfer, in which case the compatibility of HLA molecules is crucial (endogenous antigens on the white blood cells), otherwise the body may reject them. Therefore, normally, doctors use the cells of siblings with an identical HLA structure to perform this kind of procedures.

More information on anatomy lessons is available on the internet.

Golf A Sport for Rich People

Golf is increasingly popular and playing golf has become much more accessible, as well as the equipment necessary to practice it.

Play golf with the right golf clubs

 

The clubs are the main pieces of equipment in golf as they help you to adapt to different situations on the fairway. There are three types of clubs for three broad categories of strokes. The long shots require wood clubs numbered 1 to 9. The higher the number, the stronger is the stroke. High shots require iron clubs numbered 10 (pitching wedge) and 11 (sand wedge). These are used mainly to get out of the bunker or for shots to the green. Finally, the putter is a unique golf club set used on the green for the final stroke toward the hole. Be aware that a golfer can use all their golf clubs during a game. Golf reveals itself as a truly strategic game because the player can select a maximum of 14 clubs depending on the physiognomy of the course and the way of playing. As a beginner, you can buy a basic golf pack that costs about 300 USD and includes four irons and woods and a putter. Each of your clubs is numbered. You can also rent junior golf equipment on the site but it would be better to buy your own clubs if you are not a very good golfer.

Clothing and golf accessories are very important

 

There are various other accessories you need to play golf apart from the golf bag. First of all, you need several clubs to succeed different shots throughout the course and, of course, you need a bag to carry all these clubs. You can always rent a cart in order not to carry your equipment around walking as the course is about 6,000 m-7,000 m long. You can also choose an electric cart, in which case your efforts are concentrated in the beatings. Golf is a game of patience. Usually, the 18-hole course requires many hours of play. The bag is intended not only for the carrying of the clubs, but also for the storage of objects the player usually needs to be comfortable - bottled water, light food, warm clothing in case of windy conditions, raincoats and umbrellas for bad weather, etc. - and that of necessary accessories such as balls, the tee or the divot.

Golf is also about image

 

Finally, golf has its dress code and an image of prestige to defend despite its extension. There may be no strict golf attire, but there are still certain aspects related to clothing golfers should pay attention to before stepping on the tee. The typical golfer is dressed in a polo shirt with a V-neck vest and simple sport pants because they are comfortable and the risk of being too cold or too hot is very low. The golfer must also invest in shoes because they may affect the stroke and even damage the golf course. The so-called "soft spike shoes" are recommended. Finally, you should not forget about the glove. The right-handed should wear the glove on the left hand, while the left-handed should wear it on the right one.

Golf is an outdoor sport, but technological advances offer people the opportunity to play golf in the city, inside cabins with a surface of just 30 square meters with a giant touch screen that allows for lifelike simulation. The game is played in 3D mode, so you hit real balls with your real clubs. If you live in the United States of America, you can try your swing on an indoor golf course. This is perfect for practice before playing on a traditional golf course.

Finally, you must also purchase a license each season in order to be allowed to play golf even as an amateur (apart from the accessories). Now you are ready to test the course.

The fragrance of Coffee

Animal like: animal-like, such as wet coat or sweat

Ashy: like cold ashes, an attribute of the roasting

Burnt, smoky: smoky, slightly burnt, as related to wood, more often in dark rusting

Chemical, medicinal: hospital-like, or as in the pharmacy, including "Rio-taste" because it occurs in certain Brazilian coffee, rather negative

Chocolaty: chocolatey, the scent of cocoa

Caramelly: soft, caramelized sugar

Malty, toast like: roasted like oatmeal, fresh bread

Earthy: earthy, moist soil,  negative

Floral: dandelions, Jasmine, nice acid

Fruity, citric: citrus, pleasant acid

Grassy green: immature fruit, fresh grass, leaves

Nutty: nutty, fresh walnut

Rancid, rotten: rancid fats, oils, foul, negative

Rubber like: like glue, hot rubber, typical of some robusta beans

Spicy: cinnamon, cloves, curry, allspice ...

Tobacco: how fresh pipe tobacco

Winy: fruity, high acid fine

Woody: freshly split wood, fine and positive



The taste
Acidity: Fine, nice acids are typical of Arabica. It must not  be confused with the unpleasant acid from wrong or poorly roasted coffee.
Bitterness: It is important due to a number of substances that can be amplified by rusting and preparation.

Sweetness: The caramelization of sugar units

Salty:  Rare, rather undesirable (due to inaccurate cleaning of the machine)

Sour: vinegar, unpleasant, often in poorly prepared coffee


The body / The abundance
Good body: full, pleasant feeling in the mouth

Nearly no body: empty, aqueous in the mouth

Adstringency: after swallowing, astringent tones. It is often in Robusta.

Proper storage of coffee

 

Taste and aroma of coffee have natural enemies to fight with: light, oxygen and time . The less time is gone, the more aromatic is the taste of coffee. Light and oxygen can destroy more than 1,500 different components, the unique flavor of each type of coffee may disappear. To the coffee aroma, at least a chance must be given. There are some rules that should be considered:

Always buy whole beans and grind only the amount that is being required. The extra sleeve of a coffee bean is used as natural protection against light and oxygen and thus obtain the aroma.

The packaging open only when they will actually consume.

The bag is opened, remaining beans are possible, preferably, these must be stored in airtight containers, such as in a coffee can and not in the fridge . At low temperatures, you can fall to the flavor. In addition, coffee is a magnet, attracting odor smells from the environment to ail. Coffee, therefore, must never be stored with strong-smelling spices such as garlic. Garlic makes the taste of coffee pretty disgusting!